{"id":41672,"date":"2025-09-14T06:22:51","date_gmt":"2025-09-14T06:22:51","guid":{"rendered":"https:\/\/uomosul.edu.iq\/en\/science\/?p=41672"},"modified":"2025-09-14T06:22:51","modified_gmt":"2025-09-14T06:22:51","slug":"a-research-team-from-the-department-of-biology-registers-twelve-gene-mutations-in-the-global-gene-bank-ncbi","status":"publish","type":"post","link":"https:\/\/uomosul.edu.iq\/en\/science\/2025\/09\/14\/a-research-team-from-the-department-of-biology-registers-twelve-gene-mutations-in-the-global-gene-bank-ncbi\/","title":{"rendered":"A Research Team from the Department of Biology Registers Twelve Gene Mutations in the Global Gene Bank (NCBI)"},"content":{"rendered":"<article class=\"text-token-text-primary w-full focus:outline-none scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-68c65d51-fa40-8321-9479-1c5a2f0f2bff-3\" data-testid=\"conversation-turn-14\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-sm:[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-5\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"54ebf30d-c720-4977-9288-8ea3451748f2\" data-message-model-slug=\"gpt-5\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[3px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words dark markdown-new-styling\">\n<p data-start=\"162\" data-end=\"531\">In a new scientific achievement added to the record of the College of Science \u2013 University of Mosul, <strong data-start=\"263\" data-end=\"314\">Asst. Prof. Dr. Haitham Luqman Shihab Al-Hayali<\/strong>, <strong data-start=\"316\" data-end=\"354\">Dr. Mowafaq Khalil Hassan Al-Masri<\/strong>, faculty members in the Department of Biology, along with PhD student <strong data-start=\"425\" data-end=\"450\">Shaimaa Ubaid Mustafa<\/strong>, successfully registered twelve gene mutations in the Global Gene Bank (NCBI).<\/p>\n<p data-start=\"533\" data-end=\"619\">The registered mutations are listed under the following codes and accession numbers:<\/p>\n<ul data-start=\"620\" data-end=\"1658\">\n<li data-start=\"620\" data-end=\"724\">\n<p data-start=\"622\" data-end=\"724\"><strong data-start=\"622\" data-end=\"722\">HSHM, Obaid7HM, Obaid8HM, SHHM, Obaid9HM, Obaid3HM, Obaid4HM, Obaid2HM, MSHH, Obaid5HM, Obaid6HM<\/strong><\/p>\n<\/li>\n<li data-start=\"725\" data-end=\"794\">\n<p data-start=\"727\" data-end=\"794\"><em data-start=\"727\" data-end=\"792\">mutS-like protein 6 transcript variant 1 (MSH6) mRNA (PV505826)<\/em><\/p>\n<\/li>\n<li data-start=\"795\" data-end=\"883\">\n<p data-start=\"797\" data-end=\"883\"><em data-start=\"797\" data-end=\"881\">BRCA1 DNA repair associated protein 1 transcript variant 1 (BRCA1) mRNA (PV505828)<\/em><\/p>\n<\/li>\n<li data-start=\"884\" data-end=\"960\">\n<p data-start=\"886\" data-end=\"960\"><em data-start=\"886\" data-end=\"958\">KRAS proto-oncogene GTPase transcript variant b (KRAS) mRNA (PV558321)<\/em><\/p>\n<\/li>\n<li data-start=\"961\" data-end=\"1048\">\n<p data-start=\"963\" data-end=\"1048\"><em data-start=\"963\" data-end=\"1046\">APC regulator of WNT signaling pathway transcript variant 3 (APC) mRNA (PV505827)<\/em><\/p>\n<\/li>\n<li data-start=\"1049\" data-end=\"1150\">\n<p data-start=\"1051\" data-end=\"1150\"><em data-start=\"1051\" data-end=\"1148\">phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mRNA (PV530381)<\/em><\/p>\n<\/li>\n<li data-start=\"1151\" data-end=\"1227\">\n<p data-start=\"1153\" data-end=\"1227\"><em data-start=\"1153\" data-end=\"1225\">KRAS proto-oncogene GTPase transcript variant b (KRAS) mRNA (PV477844)<\/em><\/p>\n<\/li>\n<li data-start=\"1228\" data-end=\"1292\">\n<p data-start=\"1230\" data-end=\"1292\"><em data-start=\"1230\" data-end=\"1290\">phosphatase and tensin-like protein (PTEN) mRNA (PV491913)<\/em><\/p>\n<\/li>\n<li data-start=\"1293\" data-end=\"1358\">\n<p data-start=\"1295\" data-end=\"1358\"><em data-start=\"1295\" data-end=\"1356\">BRCA2 DNA repair associated protein (BRCA2) mRNA (PV491914)<\/em><\/p>\n<\/li>\n<li data-start=\"1359\" data-end=\"1423\">\n<p data-start=\"1361\" data-end=\"1423\"><em data-start=\"1361\" data-end=\"1421\">phosphatase and tensin-like protein (PTEN) mRNA (PV296016)<\/em><\/p>\n<\/li>\n<li data-start=\"1424\" data-end=\"1491\">\n<p data-start=\"1426\" data-end=\"1491\"><em data-start=\"1426\" data-end=\"1489\">tumor protein p53 transcript variant 1 (TP53) mRNA (PV505825)<\/em><\/p>\n<\/li>\n<li data-start=\"1492\" data-end=\"1556\">\n<p data-start=\"1494\" data-end=\"1556\"><em data-start=\"1494\" data-end=\"1554\">phosphatase and tensin-like protein (PTEN) mRNA (PV505824)<\/em><\/p>\n<\/li>\n<li data-start=\"1557\" data-end=\"1658\">\n<p data-start=\"1559\" data-end=\"1658\"><em data-start=\"1559\" data-end=\"1656\">phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mRNA (PV491915)<\/em><\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1660\" data-end=\"1695\">The registered mutations include:<\/p>\n<ul data-start=\"1696\" data-end=\"2191\">\n<li data-start=\"1696\" data-end=\"1759\">\n<p data-start=\"1698\" data-end=\"1759\">Two mutations in the <strong data-start=\"1719\" data-end=\"1729\">PIK3CA<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<li data-start=\"1760\" data-end=\"1821\">\n<p data-start=\"1762\" data-end=\"1821\">One mutation in the <strong data-start=\"1782\" data-end=\"1791\">BRCA1<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<li data-start=\"1822\" data-end=\"1883\">\n<p data-start=\"1824\" data-end=\"1883\">Two mutations in the <strong data-start=\"1845\" data-end=\"1853\">KRAS<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<li data-start=\"1884\" data-end=\"1943\">\n<p data-start=\"1886\" data-end=\"1943\">One mutation in the <strong data-start=\"1906\" data-end=\"1913\">APC<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<li data-start=\"1944\" data-end=\"2004\">\n<p data-start=\"1946\" data-end=\"2004\">One mutation in the <strong data-start=\"1966\" data-end=\"1974\">MSH6<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<li data-start=\"2005\" data-end=\"2068\">\n<p data-start=\"2007\" data-end=\"2068\">Three mutations in the <strong data-start=\"2030\" data-end=\"2038\">PTEN<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<li data-start=\"2069\" data-end=\"2130\">\n<p data-start=\"2071\" data-end=\"2130\">One mutation in the <strong data-start=\"2091\" data-end=\"2100\">BRCA2<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<li data-start=\"2131\" data-end=\"2191\">\n<p data-start=\"2133\" data-end=\"2191\">One mutation in the <strong data-start=\"2153\" data-end=\"2161\">TP53<\/strong> gene (and protein sequence)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"2193\" data-end=\"2518\">The samples were collected from patients with colon cancer who were examined by specialized physicians. This achievement represents a significant contribution to enriching global genetic databases and reflects the research efforts of the Department of Biology in the fields of Biochemistry, Molecular Biology, and Genetics.<\/p>\n<p data-start=\"2520\" data-end=\"2624\" data-is-last-node=\"\" data-is-only-node=\"\">We wish our faculty members and students continued success in their scientific and academic endeavors.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"flex min-h-[46px] justify-start\"><\/div>\n<div class=\"mt-3 w-full empty:hidden\">\n<div class=\"text-center\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>In a new scientific achievement added to the record of the College of Science \u2013 University of Mosul, Asst. Prof. Dr. Haitham Luqman Shihab Al-Hayali, Dr. Mowafaq Khalil Hassan Al-Masri, faculty members in the Department of Biology, along with PhD student Shaimaa Ubaid Mustafa, successfully registered twelve gene mutations in the Global Gene Bank (NCBI). The registered mutations are listed under the following codes and accession numbers: HSHM, Obaid7HM, Obaid8HM, SHHM, Obaid9HM, Obaid3HM, Obaid4HM, Obaid2HM, MSHH, Obaid5HM, Obaid6HM mutS-like protein 6 transcript variant 1 (MSH6) mRNA (PV505826) BRCA1 DNA repair associated protein 1 transcript variant 1 (BRCA1) mRNA (PV505828) KRAS proto-oncogene <a href=\"https:\/\/uomosul.edu.iq\/en\/science\/2025\/09\/14\/a-research-team-from-the-department-of-biology-registers-twelve-gene-mutations-in-the-global-gene-bank-ncbi\/\"> [Read More]<\/a><\/p>\n","protected":false},"author":21,"featured_media":41673,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-41672","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/posts\/41672","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/users\/21"}],"replies":[{"embeddable":true,"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/comments?post=41672"}],"version-history":[{"count":1,"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/posts\/41672\/revisions"}],"predecessor-version":[{"id":41674,"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/posts\/41672\/revisions\/41674"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/media\/41673"}],"wp:attachment":[{"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/media?parent=41672"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/categories?post=41672"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/uomosul.edu.iq\/en\/science\/wp-json\/wp\/v2\/tags?post=41672"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}