College of Science

The Chemistry Department of the College of Sciences discussed today, Thursday, December 11, 2025, the doctoral thesis submitted by the student (Shahla Shafiq rizouki) and tagged “assessment of the physiological role of sclerostin in coronary heart patients”, in the presence of the dean of the College, Prof. Dr. Hiyam Adel Ibrahim, the administrative and Scientific Assistants of the dean and the head of the Chemistry Department, Assistant Professor Dr. Firas Ahmed the esteemed and a number of the best college teachers.

The discussion committee consisted of Mr. Prof. Dr. Fazel Jawad al-tohma (chairman) and Prof. Dr. Mona Hussein Ali (member) and Assistant Prof. Dr. Mohamed Bahri Hassan (member) and Assistant Prof. Dr. Jahan Abdul Wahab Mohammed (member) and Assistant Prof. Dr. Ehsan Hassan Taha (member), under the supervision of Prof. Dr. Thikra Ali Alloush.

The dissertation dealt with the study of Sclerostin protein in coronary artery patients through three main axes:

The clinical axis included the collection of blood samples from 160 cases of both sexes, including 80 cases with stable coronary heart disease and 80 healthy people as a control group. The concentration of sclerostin protein was measured in both groups, and the results showed a significant decrease in the concentration of sclerostin in the blood serum of patients compared to the healthy group.in addition to sclerostin, 21 biochemical variables were measured, divided into four categories: cytokines of the interleukin-6 family, cardiac markers, blood lipid tests, and oxidative stress States. the results showed a significant increase in the three cytokines in patients compared to healthy, and a clear increase in cardiac markers was also observed.

And the second part of the study involved the isolation and purification of sclerostin.

As for the third part, whole blood samples were used for the molecular study, which included estimating the gene expression level of sclerostin using qPCR technology, and studying the most common nucleotide multiplicity (SNP) rs17882143 (C/T) in the SOST gene in patients and the control group using TETRA ARMS-PCR technology, where DNA DNA extraction was performed according to the traditional methodology, and purity and concentration were evaluated using the NanoDrop device.

At the end of the discussion, the dean of the faculty presented a letter of thanks and appreciation to Professor Dr. Fadel Jawad al Toma from the Faculty of Health and medical technologies/ future University in appreciation of his scientific efforts and active participation in the discussion of the thesis.

Congratulations to the outstanding student for this achievement and wishes our students success and reaching the highest ranks of Science and giving

Information and Government Communication Division

Thursday, December 11, 2025