College of Science

The Department of Biology Sciences at the College of Science, University of Mosul, discussed a doctoral dissertation entitled:

Role of miRNA Molecule and DNA Methylation in Regulation of Gene Expression for Circadian Rhythm Genes in Mental Disorders.

The dissertation was presented by student Zahra Jassim Ramadan. Her study addressed the role of epigenetic regulation of circadian clock genes, particularly BMAL1, CLOCK, and PER family genes, and their relationship to mental disorders in children.

The study aimed to measure the gene expression levels of these genes and demonstrate the effect of miRNA molecules and DNA methylation on their regulation. Advanced molecular and clinical techniques were employed, including qPCR, PCR, and gene sequencing, in addition to measuring melatonin and cortisol hormone levels. The results showed clear abnormalities in gene expression and methylation, which contribute to explaining circadian clock disorders associated with mental states.

The examining committee consisted of:

Professor Dr. Aqeel Hussein Ali Al-Asi – Chairman

Professor Dr. Nashat Ghaleb Mustafa Mohammed – Member

Professor Dr. Mohammed Ibrahim Khalil Ibrahim – Member

Professor Dr. Firas Hamid Akhdhir Nazal – Member

Assistant Professor Dr. Abeer Attallah Ayed Jassim – Member

Professor Dr. Oweis Muwaffaq Hamed Mohammed – Member and Supervisor

Professor Emeritus Dr. Elham Khattab Abdullah Mohammed – Member and Supervisor

At the conclusion of the examination, the committee commended the scientific value of the dissertation and its findings, which contribute to the advancement of scientific research in the fields of molecular genetics and mental disorders.

In conclusion, the Head of the Department of Biology Sciences, Professor Dr. Amjad Abdulhadi Mohammed, on behalf of the Dean of the College of Science, Professor Dr. Hiyam Adel Ibrahim, presented a letter of thanks and appreciation to Professor Dr. Aqeel Hussein Ali Al-Assi, in recognition of his attendance, active participation, and scholarly contribution to enriching the discussion and his valuable observations that contributed to evaluating the thesis and enhancing its academic rigor.

The College of Science extends its sincere wishes to our dear student and our college for continued success and further scientific contributions and academic excellence.

Media and Government Communication Division

Wednesday, January 21, 2026