College of Education for Pure Science

PH.D. Dissertation Viva in the College of Education for Pure Science entitled ” Separation and estimation of some antioxidants from a medicinal plant and study of their effect on some biochemical variables in the liver of mice infected with hydatid cyst disease “The College of Education for Pure Science, University of Mosul, has done the PH.D. Dissertation Viva entitled ” Separation and estimation of some antioxidants from a medicinal plant and study of their effect on some biochemical variables in the liver of mice infected with hydatid cyst disease “,On Sunday, November 6, 2022, the College staff including the respected Dean of the College, Assistant Professor Dr. Qais Ismail Ibrahim, the Honorable Scientific Associate and Administrative Associate, the Honorable Head of the Department of Chemistry, and a number of the college’s teachers were attended the viva. During this study, presented by the PH.D. Student Nawfal Sheet Mohammad Al-Jiboury in the Department of Chemistry, male rats were injected with 2000 live protozoa for each rat in all groups except the negative control group for a period of three months,When the third and fourth affected groups were dosed with Albizia leaf extract and Albendazole, respectively, for three months, it was found that there was a significant decrease in the level of polyamine oxidase activity, creatinine, albumin and vitamin D3 level. While there was a significant increase in the concentrations of glucose, urea and uric acid compared with the positive control group at the probability level P ≤ 0.01. The current study also included partial purification of polyamine oxidase from kidney extract and blood serum of male rats infected with hydatid cyst disease, using some biotechniques. A second experiment was designed to study the effect of different concentrations of Albizia leaf extract and albendazole, where male mice were injected with 2000 live protozoa in all groups for two months except negative control group. After the third and fourth affected groups were dosed with Albizia leaf extract and Albendazole, respectively, at concentrations (mg/k 0.05, mg/k 0.1, mg/k 0.2, mg/k 0.3, mg/k 0.4) for two months, a significant decrease in the enzyme level was observed. Polyamine oxidase and albumin concentration for all concentrations in groups treated with plant extract and albendazole compared with the positive control group. The possibility of inhibition of Albizia leaf extract on the enzyme partially purified polyamine oxidase from kidneys and blood serum of male rats was studied. The inhibitory effect of Albendazole on the activity of the purified enzyme from the kidneys of rats was also studied. The Viva committee was chaired by Prof. Dr. Shihab Yousif Ahmed Al-Bajari / Northern Technical University/ Technical Agricultural College of Mosul and the membership of Prof. Dr. Nadia Ahmed Saleh / University of Tikrit/ College of Education For Pure Sciences, Asst. Prof. Dr. Mohammad Abd Al-Hadi Jasim / University of Mosul / College of Education for Pure Science, Asst. Prof. Dr. Nashwan Ibrahim Abo / University of Mosul / College of Education for Pure Science, Asst. Prof. Dr. Nagham Qasim Kazem / University of Tikrit/ College of Science and under the supervision and membership of both Prof. Dr. Omar Younis Mohammad / University of Mosul / College of Education for Pure Science and Prof. Dr. Wathba Idris Ali/ University of Mosul / College of Education for Pure Science.