19 February، 2026

College of Science Discusses a Master’s Thesis on the Synthesis of Novel Coordination Complexes and the Evaluation of Their Biological Activity

The Department of Chemistry at the College of Science, University of Mosul, discussed a Master’s thesis on Thursday, 19 February 2026, entitled:

“Synthesis and Characterization of a Number of Transition Metal and Zinc Complexes with Thiazole-Derived Cyclic Ligands and Evaluation of Their Biological Activity.”

The thesis was presented by Alaa Abu Bakr Ali, a postgraduate student in the Inorganic Chemistry Branch. Her research focused on the synthesis of thirty novel coordination complexes alongside four fundamental thiazole-derived ligands, with the aim of investigating their structural and chemical properties and evaluating their biological activity.

The first stage of the study involved the synthesis of ligands (L1, L2) through the reaction of thiourea with substituted acetophenones in the presence of iodine as a catalyst. The second stage focused on the preparation of ligands (L3, L4) by reacting the synthesized ligands with substituted benzoyl chlorides. The third stage was dedicated to the synthesis of coordination complexes of these ligands with Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) metal ions at molar ratios of 1:1 and 1:2, resulting in a series of newly developed complexes with distinctive structural formulas.

The synthesized ligands and their complexes were characterized using a range of advanced analytical techniques, including elemental microanalysis, infrared spectroscopy (IR), electronic spectroscopy (UV-Vis), proton nuclear magnetic resonance spectroscopy (^1H-NMR), magnetic susceptibility measurements, and molar conductivity studies.

The research also assessed the biological activity of the synthesized compounds against two bacterial species, Klebsiella pneumoniae and Staphylococcus aureus. Several complexes demonstrated significant inhibitory activity, indicating their potential for future applications in pharmaceutical and biochemical fields.

The examination committee was chaired by:

Professor Dr. Amira Faris Mohammed

with the membership of:

Assistant Professor Dr. Anwar Mohammed Amin Abdullah

Lecturer Dr. Hiba Farouq Mohammed Amin

and supervised by:

Assistant Professor Dr. Farah Tariq Saeed, who also served as a member of the committee.

At the conclusion of the defense, the committee commended the scientific quality of the thesis and the significance of its findings, emphasizing their contribution to advancing chemical and biological research, particularly in the development of coordination compounds with antibacterial properties. The committee also highlighted the practical applicability of the research and its potential benefits to both the scientific and healthcare sectors.

The thesis aligns with several United Nations Sustainable Development Goals (SDGs), particularly:

  • SDG 3: Good Health and Well-Being, through contributing to the development of novel chemically active compounds that may serve as foundations for future therapeutic agents.
  • SDG 9: Industry, Innovation and Infrastructure, by supporting scientific research in coordination chemistry and the development of compounds with promising pharmaceutical applications.
  • SDG 12: Responsible Consumption and Production, through the application of carefully designed synthetic methodologies and modern analytical techniques that enhance chemical production efficiency while minimizing environmental impact.

The College of Science extends its sincere wishes to its students and academic staff for continued success and excellence, and for further achievements in their academic and professional careers.

Media and Government Communication Division

Thursday, 19 February 2026

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