A Thesis about Novel Beta-Lactamase inhibitors at the College of Pharmacy
admin_omar2023-04-14T02:32:53+00:00Dr Ahmad A Mahmood have passes the Viva voce about the Thesis he submitted to the Department of Pharmaceutical Chemistry which entitled as" Designing, Preparation and Studying the Biological Activity as Antibacterial agents of Novel Beta-Lactamase inhibitors". The study assessed the biological activities of synthesized compounds which were tested in vitro against 4 strains of β-lactamase G(+)ve and G(-)ve pathogenic bacteria, in addition to test their anti β-lactamases activities and comparing them with that of clavulanic acid as a co-inhibitor with amoxicillin.The ten novel compounds (Ox3, Tz5, Tz7, Tz8, Mb1, Mb4, Mb9, Mb10, Mb14 and Ad3) showed strong β-lactamase inhibitory activities [Read More]